The following are known Game Genie Codes for Duke Nukem 3D on SEGA Genesis.

• Protection From All Enemy Attacks
  AVHA-AA6A
• Large Medkits Restore 100 Health Points (Instead of 30)
  NT2T-AAGY
• Infinite Shotgun Ammo
  AVBA-AA6R
• Infinite Chaingun Ammo
  AVCA-AA76
• Infinite RPG Ammo
  AVCT-AA4G
• Infinite Devastator Ammo
  AVDA-AA5L
  AVDA-AA76

Note: Do not combine any of the 5 codes below.

• Start A New Game With 200 Pistol Ammo (Instead of 48 Bullets)
  3A1A-AAHG
• Start A New Game With 48 Shotgun Shells (Instead of 48 Bullets)
  PA1A-BL1L
• Start A New Game With 48 Chaingun Ammo (Instead of 48 Bullets)
  PJ1A-BL1L
• Start A New Game With 48 RPG Ammo (Instead of Bullets)
  PT1A-BL1L
• Start A New Game With 48 Devastator Ammo (Instead of Bullets)
  RA1A-BL1L