The following are known Game Genie Codes for Who Framed Roger Rabbit on Nintendo Entertainment System (NES).

• 1 Life
  PESSSYLA
• 6 Lives
  TESSSYLA
• 9 Lives
  PESSSYLE
• Never Lose A Life Except In Punch Lines
  SXVOYIVG
• Never Lose A Life In Punch Lines
  SZSZXYVG
• Infinite Continues
  SXKELNVK
• Harder To Build Strength
  PAUKXTGA
• Strength To Full Instantly
  EPUKXTGA
• Conspiracy Code
  UZLOSS
  Note: Someone locked the door!
• What The?!?!
  KGLOSS
  Note: I recommend getting caught by the weasels and then really seeing some weirdness afterwards.