The following are known Game Genie Codes for Star Trek 25th Anniversary on Nintendo Entertainment System (NES).

• LEOOVGYE
  Kirk has more energy than usual
• GEOOVGYA
  Kirk has less energy than usual
• LAUXYAYE
  McCoy has more energy than usual
• GAUXYAYA
  McCoy has less energy than usual
• LAUZTAYE
  Spock has more energy than usual
• GAUZTAYA
  Spock has less energy than usual
• LAVZLAYE
  Security has more energy than usual
• LAKXAAYE
  Geologist has more energy than usual
• GAKXAAYA
  Geologist has less energy than usual
• LASXZAYE
  Biologist has more energy than usual
• GASXZAYA
  Biologist has less energy than usual
• LASZPAYE
  Historian has more energy than usual
• GASZPAYA
  Historian has less energy than usual
• YEKUYPGA
  McCoy gives full energy to injured party