The following are known Game Genie Codes for Mega Man 6 on Nintendo Entertainment System (NES).

• AAUKVIZA
  Start with 1 life
• IAUKVIZA
  Start with 6 lives
• AAUKVIZE
  Start with 9 lives
• SXEEXTVG
  Infinite lives but note that you can sometimes die and go to another part of the game
• GXEAKYST
  Infinite energy except for fires, falling into pits and spikes will still kill you
• LOOEKGPP
  Normal shots do more damage
• TOKENGLP
  Mega-Shots do more damage