The following are known Game Genie Codes for Mega Man 5 on Nintendo Entertainment System (NES).

• GXSEYZSA
  Infinite energy
• GXXAAIVG
  Infinite lives
• XAKSUTEA
  Start with at least 2 Energy Tanks
• VAKSUTEA
  Start with at least 6 Energy Tanks
• GZSATPVG
  Infinite Energy Tanks on pick-up
• XASIOTEA
  Start with at least 2 Mega-Tanks
• VASIOTEA
  Start with at least 6 Mega-Tanks
• GXSEPZVG
  Infinite Mega-Tanks on pick-up
• PEVLLPGA
  Starting weapons use less energy
• OVNLZISV + OTKPYISV
  Infinite energy for most weapons
• YEXETAIA + ONUELEUN
  Super-Jump
• PEXETAIA + NNUELEUY
  Mega-Jump