The following are known Game Genie Codes for Ghostbusters II on Nintendo Entertainment System (NES).

• Infinite Lives
  SUKYAUVS
• Start With 1 Life
  AAXVGGLA
• Start With 6 Lives
  IAXVGGLA
• Start With 9 Lives
  AAXVGGLE
• Infinite Continues
  SZXPSXVK
• Triple Continues
  TAEGTAZA
• Rapid-Firing Proton Rifle
  ZEEOOXYO
• All Ghostbusters Can Mega-Jump
  KYSOKXVN
• Shield Lasts Longer (Car Scenes)
  NNXXAPAS
• Infinite Shield (Car Scenes)
  SZOXLNVK