The following are known Game Genie Codes for Alien Syndrome on Nintendo Entertainment System (NES).

• Infinite Time
  SZUNYXVK
• Set Timer To 440
  GUONPPLL
• Both Players (1 Life)
  PAOGPIGA
• Both Players (8 Lives)
  AAOGPIGE
• Start With Flame Thrower
  PAVKGIAA
• Start With Fireball
  ZAVKGIAA
• Start With Laser
  LAVKGIAA
• Don’t Lose Life When Shot Or Touched
  AEEKXONY
• Don’t Lose Life From Falling Down Holes
  AANGVXNY
• 1 Life After Continue
  PEXGGLGA
• 8 Lives After Continue
  AEXGGLGE
• Start On Round 2
  PENNELAP
  KUNNXLAA
  LENNULAZ
• Start On Round 3
  ZENNELAP
  KUNNXLAA
  LENNULAZ
• Start On Round 4
  LENNELAP
  KUNNXLAA
  LENNULAZ
• Start On Round 5
  GENNELAP
  KUNNXLAA
  LENNULAZ
• Start On Round 6
  IENNELAP
  KUNNXLAA
  LENNULAZ
• Start On Round 7
  TENNELAP
  KUNNXLAA
  LENNULAZ