The following are known Game Genie Codes for The Simpsons: The: Bart vs. the Space Mutants on SEGA Genesis.

• Infinite Energy
  D2RT-AA6N
• Start With 1 Life
  AEBT-AADG
• Start With 4 Lives
  ATBT-AADG
• Start With 5 Lives
  AYBT-AADG
• Start With 6 Lives
  A2BT-AADG
• Start With 7 Lives
  A6BT-AADG
• Start With 8 Lives
  BABT-AADG
• Start With 9 Lives
  BEBT-AADG
• Unlimited Lives
  A2RT-AA6N
• Start On Level 2
  AJBT-AADW
• Start On Level 3
  ANBT-AADW
• Start On Level 4
  ATBT-AADW
• Start On Level 5
  AYBT-AADW
• Enemy Hits And Timer Have No Effect
  AJRT-AA4N
  Note: This does not change falling in quicksand pits.
• Unlimited Cherry Bombs After You Buy One
  AAXA-BJ5L
• Unlimited Rockets After You Buy One
  AAXA-BJ6J
• Unlimited Spray Paint Once You Get It
  FJ0A-AA2G
• Stop Timer On Level 3 Door Puzzle
  E3AT-AA68
• Need 1 Goal On Level 1
  AH0A-CAGE
• Need 5 Goals On Level 1
  A10A-CAGE
• Need 10 Goals On Level 1
  CD0A-CAGE
• Need 15 Goals On Level 1
  C10A-CAGE
• Need 20 Goals On Level 1
  ED0A-CAGE
• Need 1 Goal On Level 2
  AECT-EAA6
• Need 5 Goals On Level 2
  AYCT-EAA6
• Need 10 Goals On Level 2
  CACT-EAA6
• Need 15 Goals On Level 2
  CYCT-EAA6
• Need 20 Goals On Level 2
  EACT-EAA6
• Need 1 Goal On Level 3
  AERT-EACG
• Need 5 Goals On Level 3
  AYRT-EACG
• Need 15 Goals On Level 3
  CYRT-EACG
• Need 20 Goals On Level 3
  EART-EACG
• Need 28 Goals On Level 3
  FART-EACG
• Need 30 Goals On Level 3
  GART-EACG
• Need 1 Goal On Level 4
  AE4A-EAD0
• Need 2 Goals On Level 4
  AJ4A-EAD0
• Need 3 Goals On Level 4
  AN4A-EAD0
• Need 4 Goals On Level 4
  AT4A-EAD0
• Need 5 Goals On Level 4
  AY4A-EAD0