The following are known Game Genie Codes for Spider-Man: The Animated Series on SEGA Genesis.

• Start With No Blue Web
  AA6T-RAD2
• Start With More Blue Web
  NA6T-RAD2
• Start With No Red Web
  AA6T-RAD6
• Start With More Red Web
  NA6T-RAD6
• Start With No Red Grenades
  AA6T-RAEC
• Start With More Red Grenades
  AA6T-RAEC
• Start With No Blue Grenades
  AA6T-RAEJ
• Start With More Blue Grenades
  NA6T-RAEJ
• Start With 1 Life
  AA7A-RADA
• Start With 10 Lives
  BE7A-RADA
• Start With Mega Lives
  NA7A-RADA
• Webs Worth 0
  ADWT-NAAY
• Webs Worth 1
  AHWT-NAAY
• Webs Worth 15
  D9WT-NAAY
• Webs Worth 25
  DHWT-NAAY
• Both Webs And Bombs Are Infinite
  AAXT-RAHR
• Invincibility
  GJAA-C33C