The following are known Game Genie Codes for Ghostbusters on SEGA Genesis.

• BWST-AA54
  Protection from most damage
• 96CT-BTAR
  Start with 24 life bar ticks instead of 16
• 96CT-A2AR
  Start with 12 life bar ticks
• 96CT-ATAR
  Start with 8 life bar ticks
• 96CT-AJAR
  Start with 4 life bar ticks
• ATCT-AAAG
  Start with 5 rounds
• AYCT-AAAG
  Start with 6 rounds
• A2CT-AAAG
  Start with 7 rounds
• A6CT-AAAG
  Start with 8 rounds
• BACT-AAAG
  Start with 9 rounds
• BECT-AAAG
  Start with 10 rounds
• 96CT-BYA0
  Start with 26 energy bar ticks
• 96CT-A2A0
  Start with 12 energy bar ticks
• 96CT-AJA0
  Start with only 4 energy bar ticks
• ACTT-ACH6
  $10 ghosts are worth $100
• ACTT-BAH6
  $10 ghosts are worth $1,000
• ACTT-BAS6
  $10 ghosts are worth $3,000
• ACTT-AEH8
  $20 ghosts are worth $200
• ACTT-AAS8
  $20 ghosts are worth $2,000
• ACTT-BA18
  $20 ghosts are worth $5,000
• ACVA-AGAA
  $30 ghosts are worth $300
• ACVA-BAJA
  $30 ghosts are worth $3,000
• ACVA-BATA
  $30 ghosts are worth $5,000
• ACVA-ALAC
  $50 ghosts are worth $500
• ACVA-BATC
  $50 ghosts are worth $5,000
• AV0T-AA4C
  Infinite bombs
• NNCT-AABN
  Start with 99 bombs
• CJCT-AABN
  Start with 18 bombs
• EYCT-AABN
  Start with 37 bombs
• AACT-AABN
  Start with 0 bombs