The following are known Game Genie Codes for The Simpsons: Itchy & Scratchy on Nintendo Game Boy.

• 009-0E9-E6E
  Always get a Hole-in-One
• 00A-24D-E6E
  Infinite Lives
• 000-7D9-CCE
  Start with 1 Life
• 040-7D9-CCE
  Start with 5 Lives
• 0E0-7D9-CCE
  Start with 15 Lives
• 00A-24A-3BE
  You are invincible after getting hit
• 00A-07A-C49
  Invincibility