The following are known Game Genie Codes for Serpent on Nintendo Game Boy.

• 057-C9D-E6A
  Start with 5 missiles
• 087-C9D-E6A
  Start with 8 missiles
• 0F7-C9D-E6A
  Start with 15 missiles
• 00F-B0E-E69
  Infinite missiles on pick-up
• 157-C6D-4CA
  Start with a smaller tail
• 407-C6D-4CA
  Start with a longer tail