The following are known Game Genie Codes for Adventure Island II on Nintendo Game Boy.

• 006-DDB-E6E
  Infinite lives
• 000-6DB-E66
  Start with 1 life
• 050-6DB-E66
  Start with 6 lives
• 080-6DB-E66
  Start with 9 lives
• 00E-28F-E6E
  No gradual loss of energy, in other words no timer, but energy can still be drained by obstacles and enemies
• 3C0-37B-5D4
  Start with 1 of each power-up
• 00D-51A-E6E
  Once you collect any non-throwable object, you cannot lose it from menu
• 080-57B-E6E
  Start on level 1-4